Linear 1 3-diarylpropanoids
Medchemexpress LLC (R)-(-)-1,2-propanediol | 4254-14-2 | MFCD00066248 | 25g
(R)-(-)-1 2-Propanediol is a (R)-enantiomer of 1 2-Propanediol that produced from glucose in Escherichia coli expressing NADH-linked glycerol dehydrogenase genes[1]
AdipoGen Phloretin
Chemical. CAS 60-82-2. Formula C15H14O5. MW 274.27. Phloretin is a natural dihydrochalcone, originally identified from the apple tree, and is a metabolite of phlorizin. It has numerous pharmacological effects, including anti-inflammatory, antidiabetic, anticancer, antimicrobial, hepatoprotective, neuroprotective and cytoprotective properties. Phloretin is a potent antioxidant, scavenging peroxynitrite ONOO- and/or suppressing lipid peroxidation, which contributes to the many biological properties. Phloretin has anti-aging and depigmenting effects, making it also attractive for dermatological research and application. Phloretin attacks a number of molecular targets, modulating different intracellular signaling pathways, including NF-kappaB, MAPK, Nrf2, and AMPK. It can modulate Ca2 channels, PKC, GLUTs, SGLTs and other targets. The anticancer potential is based on antiproliferative, proapoptotic, antimetastatic, and antiangiogenic activities.
AdipoGen Phloretin
Chemical. CAS 60-82-2. Formula C15H14O5. MW 274.27. Phloretin is a natural dihydrochalcone, originally identified from the apple tree, and is a metabolite of phlorizin. It has numerous pharmacological effects, including anti-inflammatory, antidiabetic, anticancer, antimicrobial, hepatoprotective, neuroprotective and cytoprotective properties. Phloretin is a potent antioxidant, scavenging peroxynitrite ONOO- and/or suppressing lipid peroxidation, which contributes to the many biological properties. Phloretin has anti-aging and depigmenting effects, making it also attractive for dermatological research and application. Phloretin attacks a number of molecular targets, modulating different intracellular signaling pathways, including NF-kappaB, MAPK, Nrf2, and AMPK. It can modulate Ca2 channels, PKC, GLUTs, SGLTs and other targets. The anticancer potential is based on antiproliferative, proapoptotic, antimetastatic, and antiangiogenic activities.
Apexbio Technology LLC Naringenin 480-41-1 100mg
Naringenin (CAS 480-41-1) is a small-molecule inhibitor designed to modulate inflammatory and antiviral pathways thereby regulating cellular inflammatory responses and viral replication Naringenin exerts its biological activity primarily through inhibition of the NF- B pathway resulting in reduced inflammatory cytokine production Additionally it demonstrates antioxidative properties by scavenging reactive oxygen species (ROS) In in vitro studies naringenin exhibits inhibition of dengue virus replication with reported IC50 values ranging from approximately 52 64 M to 143 M depending on experimental conditions and viral strains Based on these pharmacological properties naringenin holds research potential in inflammation oxidative stress-related cellular models and dengue virus infection studies
Medchemexpress LLC 2-hydroxychalcone | 644-78-0 | 98.1% | 10MM 1ML
2-hydroxychalcone | 644-78-0 | 98.1% | 10MM 1ML
Medchemexpress LLC Rac-brassinazole | 224047-41-0 | 5 MG
Rac-brassinazole is a triazole-type inhibitor of brassinosteroid biosynthesis that targets CYP90B and is used in research to modulate BR signaling pathways.
- Triazole-type brassinosteroid biosynthesis inhibitor.
- CAS 224047-41-0.
- Molecular formula C18H18ClN3O.
- Molecular weight 327.81 g/mol.
- Appearance: solid.
- Solubility: DMSO 50 mg/mL; in vivo formulations include DMSO/PEG300/Tween-80/saline and DMSO/corn oil.
- Storage: powder -20°C (3 years) or 4°C (2 years); in solvent -80°C (6 months) or -20°C (1 month).
TARGETMOL CHEMICALS INC Dapagliflozin 2S-1 2-propanedi
Also available in 1 mL, 10 mg, 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. Dapagliflozin ((2S)-1,2-propanediol, hydrate) (BMS-512148 (2S)-1,2-propanediol, hydrate) is a selective, orally active inhibitor of the renal sodium-glucose co-transporter type 2 (SGLT2), in development for treating type 2 diabetes mellitus (T2DM). It inhibits SGLT2, responsible for at least 90% of glucose reabsorption in the kidney. Purity 99.39%